I am using Clarrise 4 & 5 in my i9-9900k. when I use the point cloud layer then Clarisse crashed and I use it in my other Ryzen 3 computer and its work perfectly. I don't know why it's not working in my i9 pc.
If you manage to reproduce this crash every time, you could fill a bug report here https://www.isotropix.com/user/bugtracker , specifying all the details and attaching your scene